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Gougelet et al

These pleiotropic actions of theaflavins are mediated through the modulation of various cellular signaling pathways, such as the activation of nuclear factor erythroid 2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1) signaling cascade and the inhibition of mitogen-activated protein kinase (MAPK) signaling [16]

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Dixon SJ, Winter GE, Musavi LS, Lee ED, Snijder B, Rebsamen M et al (2015) Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death