glutathione heart disease and Cardiovascular Health A) Glutathione (GSH) (B) Malondialdehyade

Since ferroptosis was initially documented more than ten years ago, 11 accumulating data suggests that it is involved in a variety of biological processes, including tumor growth, immune escape, neuron loss, muscle atrophy, and ischemia-reperfusion

By degrading GSH, CHAC1 perturbs redox homeostasis and can effectively blunt the NRF2-driven cytoprotective response

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Future studies should prioritize the development of advanced experimental models to better replicate the chronic nature and complexity of neurodegenerative diseases