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SIRT1 activation promotes numerous anti-aging effects including enhanced mitochondrial biogenesis, improved stress resistance, reduced inflammation, and activation of cellular quality control mechanisms that remove damaged proteins and organelles

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Dysregulation of the coagulation system has been strongly suggested as a key driver of long COVID and this was the most significantly dysregulated pathway in our cohort with brain fog 32,38

Both peptides also show overlapping anti-inflammatory signals in separate studies, with each associated with reduced pro-inflammatory cytokines such as IL-6 and TNF-alpha in animal models