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Obese hypertensive rats presented with significantly increased levels of serum inflammatory cytokine including, IL-1, IL-6, IL-12, IL-18 and TNF-, when compared to the lean group

318 Hypoglycemic agents for patients with T2D and CKD CKD, diagnosed by a persistent increase in urinary albumin excretion (albuminuria), a low estimated glomerular filtration rate (eGFR), or other manifestations of kidney damage, may be a consequence of DN and nondiabetic nephropathy coincident with T2D

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