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Treatment frequency can vary, but many clinics recommend weekly injections for optimal results

B12 injections for pernicious anaemia Harvard Health Publishing explains that intramuscular B12 injections are particularly helpful for treating pernicious anaemia

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Further, those with higher B12 levels and taking high dose vitamins had better outcomes with stroke, death, and heart events compared to those with lower B12 levels and taking low dose vitamins (3)