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Discussion: Our findings suggest that CB-839 has limited efficacy in CLL treatment and shows limited synergy in combination with widely used CLL drugs

Decreases oxyradical damage - Glutathione detoxifies reactive oxygen radicals by giving them an electron which effectively neutralizes them, or glutathione joins with the oxyradical which again neutralizes it

So even the proposed mechanism does not predict an instant effect and none of this is human data

[13] on microinjection studies performed with various fluorochromes, including monochlorobimane, showed that GSH conjugates can preferentially localize to nuclei [13]

Trials 2 , e21 (2007)