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Oct 12 : PepGens Phase I myotonic dystrophy type 1 (DM1) trial is cleared to begin in the U.S

Further experimental studies and clinical trials are now necessary to document the relative importance of the oxidant stress caused by an altered redox potential associated with an elevation of homocysteine level, in comparison with alternative molecular mechanisms

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While these mechanisms support their use in skincare, most evidence comes from laboratory or limited clinical studies rather than large-scale trials on topical use

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