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Description

In preclinical models, chimeric antigen receptor (CAR)-macrophages (CAR-M) targeting the urokinase plasminogen activator receptor (uPAR), a cell-surface receptor upregulated in HSCs in cirrhotic human livers, demonstrated efficacy in reducing liver fibrosis (180)

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10.1097/HJH.0000000000001665 128 YokoyamaK.ImuraA.OhkidoI.MaruyamaY.YamazakiY.HasegawaH.et al (2012)

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Puumala et al., 2024

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DSS, dextran sulfate sodium

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