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D., Fazekas, A., Dobo-Nagy, C., Sikiric, P., & Varga, G

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A chromatin remodeling checkpoint of diet-induced macrophage activation in adipose tissue

Structural insights To gain a deeper understanding of the molecular mechanisms and biological significance of lactylation, we provide here a comparative overview of the structures of known writer enzymes (which add lactyl groups) and eraser enzymes (which remove lactyl groups) involved in lactylation

Low levels are associated with increased fatigue, weakened immunity, slower recovery, inflammation, and higher risk for chronic diseases