10.3748/wjg.v27.i25.3837 29 LiuZ.SunC.TaoR.XuX.XuL.ChengH.et al (2016)
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The acetyl group protects this tripeptide from premature breakdown in your digestive system, allowing it to reach your cells in higher concentrations where it supports healthy oxidative balance and helps maintain healthy liver and respiratory function
Data in other groups were normalized against that in control group
Under oxidative stress and induced by excessive ROS generation, Nrf2 is released from its inhibitor Keap1, allowing its translocation into the nucleus (Kasprzak et al., 2020), where it binds to the antioxidant response element (ARE) present in the DNA sequence of numerous antioxidant enzymes like glutathione-S-transferase, -glutamyl cysteine synthetase (glutamate cysteine ligase), heme oxygenase 1, and paraoxonase-1 inducing their transcription, managing the phase II response to oxidative stress (Kasprzak et al., 2020)