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Importantly, reconstitution of CHAC1-deficient cells with either untargeted or mitochondrially-targeted CHAC1 fully reversed this protective effect (Fig

In addition to its antioxidant effects and promotion of glutathione synthesis, its also a powerful anti-inflammatory compound that can reduce inflammatory signaling in cells

Although its function continues to be elucidated, SELENOF was found to interact with the endoplasmic reticulum UDP-glucose:glycoprotein glucosyltransferase (UGGT), an enzyme involved in the quality control of glycoprotein folding in the endoplasmic reticulum (30, 31)

The molecules exhibit an antimicrobial activity against bacteria, viruses, and eukaryotic pathogens with different specificities and potencies depending on the structure and amino-acid composition of the peptides