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Moreover, the temperature of the medium cannot be so high that the stability of the particular agent being incorporated in the microspheres is adversely affected

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If side effects like stomach upset or flushing are bothersome, the dosing schedule might be adjusted (e.g

On the other hand, the treatment policity estimand was used to evaluate the treatment effect for all randomized participants regardless of whether the trial was discontinued early or rescue medicien was used [2]

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