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The main enzymes involved in enzymatic reactions are uncoupled endothelial nitric oxide synthase (eNOS), NADPH oxidase (NOX), xanthine oxidase (XO), arachidonic acid (ARA), peroxidase, and metabolic enzymes such the cytochrome P450 system, cyclooxygenase, and lipoxygenase

Together, this suggests that altered PfK13 modulates the levels of reduced GSH, leading to a more reducing cellular environment in artemisinin-resistant parasites

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"Stem cell therapy for lung fibrosis conditions"