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BPC 157 or saline medication was given intraperitoneally, just before saline volume (1 mL/rat) application into the superior sagittal sinus, right external jugular vein or inferior caval vein

BPC-157 showed a dose-dependent effect compared to the control during phase 1 but showed little effect during phase 2 in the present study

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Both subcutaneous injection protocols and direct intra-articular joint injections are used depending on the condition and its severity

Mirabegron, a beta3-adrenoceptor agonist, is currently under investigation as an alternative strategy to achieve weight loss by inducing browning of subcutaneous white adipose tissue and increasing energy expenditure