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As Yale University historian Peter Swenson recounts in his seminal book Disorder: A History of Reform, Reaction, and Money in American Medicine , until the 1920s the drug industry was one of the AMAs bitterest enemies, with reformer Simmons warning that working with pharmaceutical advertisers was about the same as Faust trying to make a deal with Mephistopheles. After 1924, however, under Simmons successor Morris Fishbein, MD (1889-1976), drug advertising accounted for an ever-increasing share of the AMAs operating expenses

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Coronary heart disease is the leading cause of death and disability globally

A RAND Study (Cambridge: Harvard University Press, 1991)

Participants ages varied widely, from 18 years to over 50 years, with female representation ranging from 34100%