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Pharmacokinetics: Cyanocobalamin is administered intranasally, orally, and parenterally, while hydroxocobalamin is administered only parenterally. Once absorbed, vitamin B12 is highly bound to transcobalamin II, a specific B-globulin carrier protein and is distributed and stored primarily in the liver as coenzyme B12. The bone marrow also stores a significant amount of the absorbed vitamin B12. This vitamin crosses the placenta and is distributed into breast milk. Enterohepatic recirculation conserves systemic stores. The half-life is about 6 days (400 days in the liver). Elimination is primarily through the bile; however, excess cyanocobalamin is excreted unchanged in the urine
if you develop symptoms like hives, difficulty breathing, chest tightness, or severe dizziness after an injection, seek medical attention, as those could indicate an allergic reaction (which is extremely uncommon)
Biohacker Microdosing Dose: 2.5 5 mg (= 815 clicks) Duration: 4 weeks Frequency: Every other day Cycle Interval: Repeat monthly Goal / Description: Evaluates mild NAD+ upregulation and metabolic activation
Cells characterized by rapid division (epithelial cells, bone marrow, myeloid cells) appear to have the greatest requirement for methylcobalamin
