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Crevensten G, Walsh AJ, Ananthakrishnan D, Page P, Wahba GM, Lotz JC, Berven S: Intervertebral disc cell therapy for regeneration: mesenchymal stem cell implantation in rat intervertebral discs

519 Ultimately, GLP-1RA, by regulating BMP4 and its effects on cell proliferation and metastasis, provides a promising treatment approach

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Others with chronic injuries see more gradual improvement over 612 weeks of consistent use

However, the clinical transformation of natural peptides is limited by stability and delivery efficiency, while synthetic peptides need to solve the problems of species-specific differences and long-term safety verification