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Targeted activation of Nrf2 inhibits ROS production, thereby suppressing the proliferation and migration of fibroblast-like synovial cells, which resemble fibroblasts in rheumatoid arthritis [156]

It protects against oxidative damage and reduces overall inflammation

The peptide has been studied for its ability to mimic some of the fat-burning activities of HGH without causing growth hormone-like side effects

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The Critical Problem: No Human Clinical Evidence As of early 2026, not a single randomized controlled trial (RCT) has been completed and published for human musculoskeletal indications