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[DOI] [Google Scholar] 32.Ayhan E., Tuna Z., Oksuz C

However, no research directly compares continuous use versus cycling protocols (such as 12 weeks on, 4-8 weeks off), leaving optimal long-term strategies somewhat uncertain

The choice of timing should therefore prioritise consistency and individual tolerance rather than attempting to optimise absorption through scheduling

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Patients with Normal Intestinal Absorption: Where the oral route is not deemed adequate, initial treatment similar to that for patients with pernicious anemia may be indicated depending on the severity of the deficiency