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Description

Reduced CYP3A4 activity could slow isotretinoin metabolism, raising plasma exposure and amplifying both efficacy and toxicity

R.ThomasH.et al (2010)

Flavonoids, the most abundant subgroup, include flavonols (e.g., quercetin), flavones (e.g., apigenin), and anthocyanins (e.g., cyanidin), known for their antioxidant and anti-inflammatory properties