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Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations COX: cytochrome c oxidase CS: citrate synthase CTNS: cystinosin GSH: glutathione GSSG: oxidized glutathione NC: nephropathic cystinosis PG: pyroglutamic acid References Gahl WA, Bashan N, Tietze F, Bernardini I, Schulman JD 1982 Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis

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For instance, genetic variations (polymorphisms) in GST genes are well-documented to influence an individuals susceptibility to certain diseases, their response to drug treatments, and their capacity to detoxify environmental toxins

Wide release: March 22, 2026

They also support research on biochemical regulation