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It also plays a significant role in downregulating key inflammatory mediators

[175] Wells Fargo had previously been investigating reports of gender bias in the division in the months leading up to the meeting

This is because hemoglobin A1C (a measure of blood sugar control) and sex hormone-binding globulin (SHBG) are inversely correlated: as A1C improves with weight loss, SHBG levels may rise, which can bind more testosterone and reduce the amount that circulates freely in the bloodstream

While not a standalone solution, it complements diet and exercise by boosting energy and metabolic function