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272 Senescent HSCs may secrete proinflammatory factors, chemokines, and proteases, which affect themselves and other cells, disrupting the homeostasis of the bone marrow microenvironment

BPC-157 Molecular FormulaC62H98N16O22 Molecular Weight1419.53 g/mol CAS Number137525-51-0 Amino Acid SequenceGly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val TB-500 Molecular FormulaC212H350N56O78S Molecular Weight4963.44 g/mol CAS Number77591-33-4 Amino Acid SequenceAc-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser Research Applications Investigated in preclinical models for combined angiogenic and cytoskeletal remodeling pathways