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One of the few clinical trials involving humans was actually able to corroborate this finding in patients following ST elevation myocardial infarction (STEMI)

Plasma oxalate as a predictor of kidney function decline in a primary hyperoxaluria cohort

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The KEGG pathway of osteoclast differentiation showed upregulated DEGs in HFD conditions and downregulated DEGs with mannose supplementation

284 Thus, successful implementation of the KD requires well-organized and consistently functioning cooperation between caregivers and patients, and clinical settings that support this cooperation