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5 Department of Medicine and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Tirzepatide is contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, those with severe hypersensitivity to tirzepatide, and should be used cautiously in patients with history of pancreatitis or severe gastrointestinal disease
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That's the double-edged sword in a sentence: the same property that makes IGF-1 LR3 powerful for stimulating muscle growth also removes the natural brakes that normally keep IGF-1 signaling safe
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