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SCFAs influence brain function through four principal mechanisms: (i) Bloodbrain barrier (BBB) modulation: SCFAs regulate tight junction protein expression, preserving BBB integrity and restricting entry of peripheral inflammatory factors (Qu et al., 2024)

This routine hits all the major aging pathways without overcomplicating things

Thyroid 19 , 13031315 (2009)

A comprehensive meta-analysis of nine casecontrol studies involving over 21,000 participants demonstrated that individuals who had ever smoked had a significantly higher risk of PBC compared to never-smokers (pooled OR: 1.31

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