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The carcinogenic effect is based on reactive metabolites of nitrosamines in the metabolism, which react with the genetic material DNA, damaging it and triggering tumors

its effects can extend through all stages of pregnancy

23 Areca nut: Areca nut is a mild stimulant, akin to coffee, that is chewed with betel leaf

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tobacco: What science says about lighting up NEW YORK (AP) - As more states make it legal to smoke marijuana, some government officials, researchers, and others worry what that might mean for one of the country's biggest public health successes: curbing cigarette smoking