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J Cell Biol 164(1):2533

Discussion Here, we showed that the intermediate metabolite -KG controls the translation of energy sensor AMPK in human liver and lung cancer cells to maintain cell survival under energy stress

STING Palmitoylation as a Therapeutic Target for Inflammatory Diseases Aberrant activation of the STING pathway has been implicated in the pathogenesis of a variety of inflammatory and autoimmune diseases including AicardiGoutires syndrome (ASG) and systemic lupus erythematosus (SLE) (186188), which are both caused by loss of function mutations in the enzyme 3 repair exonuclease I (TREX1) gene

Lancet 2:105, 1956

Swedish researchers from Karolinska Institute (the same team behind the foundational research on nitrate and beetroot) spent 8 years stabilizing the fragile plant compounds (isothiocyanates, or ITCs) that make this work