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Meanwhile, Mn 2+ catalyzed H 2 O 2 to produce toxic OH through Fenton-like reactions under the assistance of HCO 3 2- and high temperatures, which was engineered by an MS-BSA-triggered photothermal effect, potentiating a GSH depletion-prompted robust anticancer effect

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In addition, an increasing amount of research has supported a pathophysiological role for ferroptosis in the development of cardiovascular diseases, including myocardial ischemiareperfusion injury, myocardial infarction, adriamycin-mediated myocardial injury, and heart failure [69]

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