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Usage Cited in: Pharmaceuticals (Basel)

MOTS-C (Mitochondrial Open-Reading-Frame of the 12S rRNA-C) is a mitochondrial-derived peptide that plays a crucial role in metabolic regulation

The prevalence of depression varies among liver disease diagnoses, with notably higher rates in patients with MASLD and chronic hepatitis C, whereas patients with hepatitis B exhibit depression rates comparable to the general population

145 , 146 Meanwhile, exosomes seem capable of adapting to the tumor microenvironment, especially in PC, which means they might be able to overcome various physical and chemical barriers there

Since TFR1 mediates the main route of iron entry into neurons via the Tf-TFR1 complex, HIF-1-dependent TFR1 induction leads to iron influx and overload within neurons (134)