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Another group reported that the synbiotics supplements, which contained 100 mg Lactol probiotic comprised of Lactobacillus coagulants and Fructo-oligosaccharides (FOS) administered to hemodialysis patients in a randomized, double-blind, placebo-controlled trial significantly reduced total iron binding capacity in the synbiotic group

Long-term users should be assessed if symptoms of deficiency develop, with supplementation provided if deficiency is confirmed

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