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These deficiencies might be caused by many reasons, such as anorexia, lactation, stress, or overexertion

It is naturally produced in human gastric juice, but is also found in small amounts in the gastric juice of other mammals

TB-500 safety data is less extensive but similarly suggests good tolerability in preclinical models

Additionally, B12 works closely with folate (vitamin B9) in DNA and RNA synthesis, essential for the growth and function of all cells in the body

Because vitamin B 12 in supplements is not bound to protein, and because intrinsic factor (IF) is still available, the absorption of supplemental vitamin B 12 is not reduced as it is in pernicious anemia