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This creates a devastating twofold crisis for the patient: their mast cells are releasing excessive amounts of endogenous histamine due to mycotoxin triggers, while their body simultaneously loses the enzymatic ability to clear that histamine

Int J Mol Sci 23:5954

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GIP receptor activation in adipose tissue influences lipid storage and mobilization, and in the brain, it contributes to appetite regulation through mechanisms that complement GLP-1 signaling