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Pernicious anemia, a condition caused by a vitamin B12 deficiency, often goes unnoticed, leaving people feeling sluggish, weak, or even confused

after an intramuscular injection of 1,000 g of cyanoB 12 , about 150 g is ultimately retained in the body 15 Most vitamin B 12 -deficient individuals in the UK and other countries are treated with intramuscular vitamin B 12 , and vitamin B 12 replacement has been traditionally administered intramuscularly

The timeline for effectiveness depends on the individual, with benefits ranging from immediate to long-term improvements

No body composition change yet

Barrea EXCLI J 2026;25:191-203