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In preclinical studies, BPC-157 demonstrated an exceptionally wide therapeutic window with no observed toxicity even at high doses. Sikiric et al., Current Pharmaceutical Design Long-Term Safety As of now, long-term human safety data is lacking

Essentially, the clinic administering the peptide (which the patients paid for out-of-pocket) later phoned patients to ask if they felt better, and wrote up the responses

Shedding light on the cell biology of extracellular vesicles

Consequently, many clinicians combine both therapies to achieve synergistic effects, particularly in complex or chronic tendon injuries