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Cigarette Use in the United States and the Resulting Health Consequences Cigarette smoking is the leading cause of preventable disease and death in the United States and is responsible for more than 480,000 deaths per year (Ref

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This new evidence also suggests that [because of vaping] we may see an increase in respiratory disease as youth and young adults age into midlife, including asthma, COPD, and other respiratory conditions. This work was supported by the National Heart, Lung, and Blood Institute, the US Food and Drug Administrations Center for Tobacco Products (CTP), and an American Lung Association Public Policy Research Award.