Heterozygous ambra1 deficiency in mice: a genetic trait with autism-like behavior restricted to the female gender
This distinction has clinical significance for safety and therapeutic consistency
Photo Credit: Shutterstock Yes, it is glutathione, an antioxidant that does the magic
Drug-induced cardiac mitochondrial toxicity and protection: From doxorubicin to carvedilol
CB-839 (Telaglenastat), a potent, reversible, and selective small-molecule inhibitor that targets GLS-1 and has a half-maximal inhibitory concentration (IC 50 ) of 24 nM for recombinant human glutaminase C, has been investigated in solid tumors and in AML, diffuse large B-cell lymphoma, and multiple myeloma cells alone or in combination with other anticancer drugs (10, 11, 2026)