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All patients ( n = 209) with MM ( n = 41), NSCLC ( n = 91), urothelial cell carcinoma ( n = 8), renal cell carcinoma ( n = 21), head and neck cancer ( n = 28), gastric cancer ( n = 19) or Hodgkin lymphoma ( n = 1) treated with pembrolizumab or nivolumab between November 2, 2015 and October 31, 2018 at Nagoya University Hospital were included in this study, and observed until death or referral to another hospital

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Neural Structure: Lifetime use has been associated with larger brain volumes in CB1-rich regions like the caudate, putamen, and hippocampus

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