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Computational analysisviral replication models based on Recon 2.2 The viral replication reaction for SARS-CoV-2 was taken from Renz et al

Neurogastroenterol Motil (2013) 25:733e575

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Simultaneously, it activates extracellular signal-regulated kinase (ERK1/2) pathways while reducing pro-inflammatory nuclear factor kappa B (NF-B) signaling a combination that supports tissue recovery while managing inflammation