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Likewise, fully maintained spatial learning and memory of the rats in the Morris water maze test was ascribed to hippocampal synaptic plasticity and NMDA receptor function [237] involving the entorhinal and perirhinal cortices, the prefrontal cortex, the cingulate cortex, the neostriatum, and perhaps even the cerebellum in a more limited way [237]

A favorable preclinical safety profile that has not been contradicted by human pilot data

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If you have kidney disease, speak with your doctor or healthcare professional before taking vitamin B12