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While most cases of delayed cutaneous hypersensitivity have been recorded in patients who received the Moderna vaccine, a few cases have been reported by recipients of the Pfizer vaccine, says Esther Freeman, M.D., Ph.D., director of Global Health Dermatology at Massachusetts General Hospital and principal investigator for the global COVID-19 Dermatology Registry
Furthermore, increased ACE2 expression in alveolar type II pneumocytes and alveolar macrophages of individuals with severe SARS-CoV-2 disease (ARDS with diffuse alveolar damage) requiring mechanical ventilation (Baker et al., 2021) favors a concomitant increase in oxidative stress in those individuals
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