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Evaluating the effect of CD38 treatment on brain IL-1, revealed a reduction at a protein level when analyzing the cortices of these same mice, a phenomenon that was also observed when each independent experiment was separately analyzed (Fig
This is usually acquired with age and should be repaired as it can result in constant irritation and pain to the eye
Second, many available studies are characterized by small sample sizes or lack appropriate control groups, making it difficult to draw definitive conclusions about therapeutic efficacy and optimal treatment protocols
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