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Un dficit prolong peut galement provoquer une faiblesse musculaire et des douleurs articulaires , lies une mauvaise rgnration cellulaire et un dysfonctionnement du systme nerveux

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McCann MR, Tamplin OJ, Rossant J, Seguin CA: Tracing notochord-derived cells using a Noto-cre mouse: implications for intervertebral disc development

This irritancy test approach may be extended to other similar compounds or minerals and can potentially predict the in vivo skin irritation response before conducting clinical testing on human subjects