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Another study found that Qili Qiangxin Capsule can significantly reduce the left ventricular end-diastolic diameter (LVEDD) in patients with chronic heart failure, reduce the plasma vasopressin (AVP) concentration, significantly increase the plasma brain natriuretic peptide (BNP), left ventricular ejection fraction (LVEF) and 6-min walk distance, improve exercise tolerance (Wu et al., 2011