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Nicotine pouch products, as a low-risk tobacco alternative, were introduced in the early 21st century and have gradually gained popularity in markets such as Europe and America in recent years, quickly leading the market trend

Cigarette and tobacco products Twenty two different brands of cigarettes, nine popular domestic brands of cigarette (made in Iran) and thirteen popular brands of the imported cigarettes, available in the market were chosen to evaluate their nicotine content (Table 1)

"Their unchanged content over decades, as well as their small size and lack of images, undermines the current warnings' effectiveness," the FDA said in a statement

Based on the scientific evidence on ANDS, we explore benefits and harms to public health to guide practice, policy, and regulation

This makes it more difficult for users to quit