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Nutrient interactions Biotin The chemical structure of biotin is similar to that of lipoic acid, and there is some evidence that high concentrations of lipoic acid can compete with biotin for transport across cell membranes (120, 121)

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Morris JS, Luthra R, Liu Y, Duose DY, Lee W, Reddy NG, Windham J, Chen H, Tong Z, Zhang B, Wei W, Ganiraju M, Broom BM, Alvarez HA, Mejia A, Veeranki O, Routbort MJ, Morris VK, Overman MJ, Menter D, Katkhuda R, Wistuba II, Davis JS, Kopetz S , Maru DM

Thus, the PI3K/AKT signaling pathway is related to the occurrence and development of AD to a certain extent, and the pathogenesis of AD can be regulated by changing the role of the PI3K/AKT signaling pathway