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GPx activity was determined by assessing the oxidised glutathione produced in the reaction catalysed by this peroxidase at 340 nm (32)

Since taking lipoic acid with a meal decreases its bioavailability, it is generally recommended that lipoic acid be taken 30 min prior to a meal (see also Metabolism and Bioavailability) (8)

The TYR gene, involved in melanin biosynthesis in melanocytes, has been significantly associated with vitiligo in the European population.63 The roles of many susceptibility loci remain unknown, highlighting the lack of understanding in the etiopathogenesis of vitiligo, which continues to be a challenge today

Could its potential non-metabolic functions or subcellular localizationsuch as within lysosomes or other organellesmodulate lysosomal pH homeostasis and death susceptibility in a context- or tumor-type-specific manner

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