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It is at the vanguard of prospective therapeutic treatments for treating metabolic diseases, obesity, and possibly even the cellular mechanisms involved in aging because of its ability to block the enzyme Nicotinamide N-methyltransferase (NNMT)

Aging reduces NAD+ synthesis pathways while increasing consumption by enzymes like CD38 and PARPs, activated by inflammation and damage.[13][15] CD38, an immune-related enzyme, ramps up with age, breaking down NAD+ precursors