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No chronic toxicity studies have been published

[20:03] Andrew Huberman Adverse events where it's unrelated to contamination or something of that sort in the literature

Starting Considerations Beginning at the lower end of the dosing range allows observation of individual response before increasing if needed

It acts as a crucial electron donor, sacrificing its own electrons to stabilize free radicals before they can attack the mitochondrial lipid membranes

The resulting death of pericytes leaves the microvasculature continuously constricted, leading to microcirculatory failure and long-term cerebral hypoperfusion due to the contractile apparatus remaining in rigor upon pericyte death, thus reducing capillary diameter [94, 104]