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The loss of beneficial bacteria means the gut loses its natural ability to regulate the local immune system, setting the stage for widespread structural damage to the intestinal wall

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In contrast, we observed a higher arginine/proline media ratio (higher metabolite concentrations in arginine medium compared to proline medium) for succinate, cis -aconitate, citrate, norleucine, -alanine, creatinine, citramalate, lysine, aspartate, isoleucine, and 10,13-dimethyltetradecanoate in gdh3 / gdh3 mutants compared to wild type (Fig

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Particularly, intramuscular injections of the O 2 O 3 mixture have shown significant efficacy in alleviating cervicobrachial pain, with discernible reductions in VAS pain scores [65, 66]